Prevalence of Inducible Clindamycin Resistance among Community- and Hospital-Associated Staphylococcus aureus Isolates

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Prevalence of inducible clindamycin resistance among community- and hospital-associated Staphylococcus aureus isolates.

Methicillin-resistant Staphylococcus aureus (MRSA) infections have become common among both hospitalized and nonhospitalized patients. Optimal outpatient therapy for MRSA infections has yet to be determined, but this matter is complicated by the possibility of inducible macrolide-lincosamide-streptogramin B resistance (MLSBi). We studied the prevalence of MLSBi in community- and hospital-associ...

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Inducible clindamycin resistance among Staphylococcus aureus isolates

Introduction: Clindamycin is considered an useful alternate drug in penicillin-allergic patients in the treatment of skin & soft tissue infections caused by Staphylococcus aureus. Staphylococcus spp. can be resistant to erythromycin through either erm or msr A genes. Strains with erm-mediated erythromycin resistance may possess inducible clindamycin resistance but may appear susceptible to clin...

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Inducible clindamycin resistance in clinical isolates of Staphylococcus aureus.

Background: Staphylococcus aureus is one of the most important agents causing nosocomial infections. Inducible clindamycin resistance is an important concern, because common laboratory tests could not detect it. Objectives: The aim of this study was to detect the inducible clindamycin resistance by D-test method. Materials and Methods: A total of 209 clinical S. aureus isolates were collected a...

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Inducible Clindamycin Resistance in Clinical Isolates of Staphylococcus aureus

Background: Staphylococcus aureus is one of the most important agents causing nosocomial infections. Inducible clindamycin resistance is an important concern, because common laboratory tests could not detect it. Objectives: The aim of this study was to detect the inducible clindamycin resistance by D-test method. Materials and Methods: A total of 209 clinical S. aureus isolates were collected a...

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Incidence of constitutive and inducible clindamycin resistance among hospital-associated Staphylococcus aureus

Clindamycin is one of the important alternative antibiotics in the therapy of Staphylococcus aureus infections. Clinical failure of clindamycin therapy has been reported due to multiple mechanisms that confer resistance to macrolides, lincosamides and Streptogramin B (MLSB) antibiotics. In vitro routine tests for clindamycin susceptibility may fail to detect inducible clindamycin resistance due...

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ژورنال

عنوان ژورنال: Journal of Clinical Microbiology

سال: 2006

ISSN: 0095-1137,1098-660X

DOI: 10.1128/jcm.02582-05